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Titlebook: Genomic Imprinting; Methods and Protocol Andrew Ward Book 2002 Humana Press 2002

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G. Wesseling,J. W. M. Muris,C. Neefwww.mgu.har.mrc.ac.uk/imprinting/implink.html). Changes in the imprinted expression of such genes result in developmental abnormalities; in the human they are associated with several diseases and various types of cancer(.-.).
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A Transgenic Approach to Studying Imprinted Genes,le to genetic modification by homologous recombination, and there are now many examples of their use to generate transgenic mice. This chapter describes a relatively new strategy for using large genomic clones that relies on Escherichia coli-based systems.
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Bisulfite-Based Methylation Analysis of Imprinted Genes,www.mgu.har.mrc.ac.uk/imprinting/implink.html). Changes in the imprinted expression of such genes result in developmental abnormalities; in the human they are associated with several diseases and various types of cancer(.-.).
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https://doi.org/10.1007/978-94-010-1581-3usion (.). These experiments laid the foundation for the discovery and exploration of this unique form of non-Mendelian mammalian gene regulation whereby expression of genes and hence phenotype were dictated by the parent from whom they where inherited. This parent-of-origin phenomenon is known as g
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