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Titlebook: Genomic Adaptability in Somatic Cell Specialization; Marie A. DiBerardino,Laurence D. Etkin Book 1989 Springer Science+Business Media New

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Genomic Activation in Differentiated Somatic Cells, types acquire a specific cellular phenotype for performing a specialized function, no further changes usually occur. We call this the stability of the differentiated state. It is now widely accepted that the process and stability of cell specialization are under genetic control. But the frequency a
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Genomic Adaptability in Somatic Cell Specialization
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Developmental Regulation of the Heat-Shock Response,n synthesis. Stress-inducible protein synthesis can be evoked by regulation at either the transcriptional or translational levels, or both. Thus, regulation at both levels must be subject to developmental modulation.
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Neoplastic Cells Modulation of the Differentiated State,m layers of mammals, can be induced to differentiate. This indicates that the phenomenon is not rare, and it suggests the possibility that the control of differentiation could be exploited in the treatment of cancer.
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,PDA at Work—Exploring Impact in Stability,n synthesis. Stress-inducible protein synthesis can be evoked by regulation at either the transcriptional or translational levels, or both. Thus, regulation at both levels must be subject to developmental modulation.
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