Titlebook: Genome Integrity; Facets and Perspecti Dirk-Henner Lankenau Book 2007 Springer-Verlag Berlin Heidelberg 2007 Chromosom.DNA.DNA Repair.Genet

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,Wirtschafts- und Währungspolitik,plication forks . translesion synthesis at the expense of replicational fidelity, error-free bypass mechanisms are available in all organisms analyzed so far to reinstall replication without corrosive effects on the integrity of the genetic information. Reasonable models for error-free replication r

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https://doi.org/10.1007/978-3-663-13573-9re ATPase of the Rad50/SMC protein family. Rad50/SMCproteins possess an ATP-binding cassette ATPase domain and a strikingly long coiled-coil dimerization/linkerdomain. In conjunction with associated subunits, Rad50/SMC proteins form large molecular rings or tetheringstructures that are well suited t

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Deutsch-israelisches Leadership Developmentning (NHEJ) is the major pathway of DSB repair.Genetic studies in yeast, human and rodent cell lines displaying increased IR sensitivity and defects inDSB repair have provided insight in the genes involved in NHEJ. These genetic data have been confirmed andcomplemented by in vitro assays which have

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Deutsch-jüdische Kinder- und Jugendliterature of chromatin structure and nuclear architecture inthe outcome of repair has, however, only slowly emerged. Important recent developments in the field comprisethe characterization of passive and active chromatin alterations following DSB induction, the function ofchromatin modifying complexes and c

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