书目名称 | Genome Integrity | 副标题 | Facets and Perspecti | 编辑 | Dirk-Henner Lankenau | 视频video | | 概述 | First book to give a full overview on genome integrity in different species.Spans from microorganisms to humans.Addresses the connection between genome integrity and human disease.Written by an intern | 丛书名称 | Genome Dynamics and Stability | 图书封面 |  | 描述 | .Cells and viruses maintain a genome capable of multiplication, variation and heredity. A genome consists of chromosomes, each being built up of two complementary strands of nucleic acid known as DNA. Its chemical integrity, however, is under constant assault from metabolic mutagens, such as hydroxy-radicals, endonucleases, radiation, replication errors, and environmental mutagens. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. The volume begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed.. | 出版日期 | Book 2007 | 关键词 | Chromosom; DNA; DNA Repair; Genetics; Genome Dynamics; Genome Integrity; Replication; Viruses; base; chromoso | 版次 | 1 | doi | https://doi.org/10.1007/b104871 | isbn_softcover | 978-3-642-07226-0 | isbn_ebook | 978-3-540-37531-9Series ISSN 1861-3373 Series E-ISSN 1861-3381 | issn_series | 1861-3373 | copyright | Springer-Verlag Berlin Heidelberg 2007 |
The information of publication is updating
|
|