Titlebook: Genome Editing and Biological Weapons; Assessing the Risk o Katherine Paris Book 2023 The Editor(s) (if applicable) and The Author(s), unde

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More Advanced Tension Problems, actors are to use genome editing technologies to develop biological weapons. This chapter includes a critical evaluation of the pool of potential misusers of genome editing technologies and how they could obtain the tacit knowledge and skill to use the technologies through traditional and untraditi

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Windows 8 Platform Considerations,otechnology, along with progress in computing power and AI, could offer solutions to pressing global challenges in human health, agriculture, and the environment. Genome editing, namely CRISPR, is already making significant gains in many areas including clinical medicine and diagnostics. CRISPR is b

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Introduction: Rapid Technological Advancements Amid Rising Concerns of Misuse,hnologies were accompanied by rising concerns over their potential misuse. While there are concerns over the accidental, inadvertent, or even reckless misuse of these technologies, this chapter explains why this book focuses on the intentional misuse of genome editing technologies by nefarious actor

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Background: Genome Editing with Programmable Nucleases,s are ZFN and TALEN, and, more recently, CRISPR. Each of these technologies are made up of a region that recognizes specific nucleic acid sequences and another region that cleaves the nucleic acid. There are different challenges that are associated with the design and build of the technologies, as w

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Risk of Misuse Assessment: Part I,ermined by assessing the ease of acquiring hardware and software, cost, and dependence on other technologies (i.e., delivery and validation tools). Ease of misuse is determined through the skill and tacit knowledge needed to use the technologies, ways to acquire the skill and knowledge, as well as t

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Risk of Misuse Assessment: Part II,d CRISPR. The magnitude of potential harm is determined through assessing the extent that genome editing technologies could be used to make pathogens more dangerous, weaponize the human microbiome, weaponize gene drives, and augment humans. The imminence of potential misuse is assessed by determinin

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Raising the Alarm on CRISPR, actors are to use genome editing technologies to develop biological weapons. This chapter includes a critical evaluation of the pool of potential misusers of genome editing technologies and how they could obtain the tacit knowledge and skill to use the technologies through traditional and untraditi