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Titlebook: Genome Editing and Biological Weapons; Assessing the Risk o Katherine Paris Book 2023 The Editor(s) (if applicable) and The Author(s), unde

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书目名称Genome Editing and Biological Weapons
副标题Assessing the Risk o
编辑Katherine Paris
视频video
概述Introduces to the state-of-the-art genome editing techniques CRISPR, TALEN and ZFN.Assesses the risk of misuse of genome editing technologies in a comprehensive manner.Discusses applications of genome
图书封面Titlebook: Genome Editing and Biological Weapons; Assessing the Risk o Katherine Paris Book 2023 The Editor(s) (if applicable) and The Author(s), unde
描述.This monograph introduces current genome editing technologies—clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) systems, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)—and provides an assessment of the risk of misuse of these technologies based on the following parameters: accessibility, ease of misuse, magnitude of potential harm, and imminence of potential misuse. The findings from this assessment are applied to analyze and evaluate the threat posed by the intentional misuse of genome editing technologies to develop biological weapons.  Furthermore, the book discusses the implications of misuse for different applications of genome editing, such as making existing pathogens more dangerous, modifying the human microbiome, weaponizing gene drives, engineering super soldiers, and augmenting the general population to confer economic advantages.   .Technologies that enable genome editing with programmable nucleases—including CRISPR, TALEN, and ZFN—allow for the precise genetic modification of organisms and cultured cells. While these technologies are used for a variety of beneficial applications, intel
出版日期Book 2023
关键词Gene Editing; CRISPR; Biosafety; Biological Weapons; synthetic biology
版次1
doihttps://doi.org/10.1007/978-3-031-21820-0
isbn_softcover978-3-031-21822-4
isbn_ebook978-3-031-21820-0
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Pertti Saariluoma,José J. Cañas,Jaana Leikasg the ability for genome editing technologies to be exploited based on the level of maturity. The findings from part I, see Chap. ., of the assessment are combined with those of part II to determine the overall risk that genome editing technologies could be misused to intentionally develop biological weapons, see Chap. ..
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Risk of Misuse Assessment: Part I,he transferability of skill and knowledge. The findings from part I of the assessment are combined with those of part II, see Chap. ., to determine the overall risk that genome editing technologies could be misused to intentionally develop biological weapons, see Chap. ..
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Designing an All-Inclusive Democracyook will accomplish that task. Finally, the chapter introduces the framework that is applied within the book to calibrate the threat of genome editing technologies and to determine in what ways CRISPR is more worrisome than its predecessor technologies.
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Marco Cantamessa,Matteo Gualano. The purpose of this chapter is to provide background on the structure and mechanism of genome editing technologies. The technical background on ZFN, TALEN, and CRISPR serves as a foundation for the assessment of the risk of misuse of genome editing technologies.
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