| 书目名称 | Genome Editing | | 副标题 | The Next Step in Gen | | 编辑 | Toni Cathomen,Matthew Hirsch,Matthew Porteus | | 视频video | | | 概述 | Will present most recent advances.in the basic understanding of mammalian host.DNA repair mechanisms.Reviews the most promising.approaches to stimulate high efficiency gene editing.Also focuses on gen | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | .This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary diseases. It presents and evaluates the most recent advances in the understanding of mammalian host DNA repair mechanisms, such as double-strand break induced gene targeting and mutagenesis, the development of zinc-finger nucleases, genome editing for neuromuscular diseases, phase integrases, triplex forming oligonucleotides and peptide nucleic acids, aptamer-guided gene targeting, AAV gene editing via DSB repair, engineered nucleases and trinucleotide repeat diseases, and creation of HIV-resistant cells. The expertly authored chapters contextualize current developments within the history of genome editing while also discussing the current and potential safety concerns of this rapidly growing field..Genome Editing: The Next Step in Gene Therapy., the latest volume in the .American Society of Gene and Cell Therapy .series, deftly illuminates the potential of genetic engineering technology to eradicate today’s deadliest and most prolific diseases. It is ideal reading for clinicians and researchers in genetics and immunology. | | 出版日期 | Book 2016 | | 关键词 | DNA Repair Mechanisms; gene therapy; Germline; Nuclease; Mutagenesis | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-3509-3 | | isbn_softcover | 978-1-4939-8061-1 | | isbn_ebook | 978-1-4939-3509-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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发表于 2025-3-21 17:39:01
