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Titlebook: Genetics of Rare Autoimmune Diseases; Javier Martín,Francisco David Carmona Book 2019 Springer Nature Switzerland AG 2019 Genomics.Autoimm

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Ergebnisse des Sieges von Gravelotte,munity. Most of the genes associated with susceptibility to pSS have been identified because the proteins involved have been previously associated with the pathogenesis of pSS or because the genes had already been associated with another autoimmune disease such as SLE or RA. Consequently, in this ch
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,Getrennt marschieren — vereint schlagen,unidentified, and, therefore, future efforts will be necessary to gain insight into this missing heritability, as well as on the functional consequences of associated variants. In addition, the role of epigenetic modifications in the IIM pathogenesis is being currently explored. Integrating genetics
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,Eheglück Aus Neurologischen Gründen,r from understanding the genetic implication in the disease. The determination of the “missing heritability,” the genetic factors that lead to the heterogeneity of the disease, the functional effects of the associated variants, and the definition of the pathways altered in MS are the actual focus of
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https://doi.org/10.1007/978-3-030-03934-9Genomics; Autoimmunity; Biomarkers; Systemic sclerosis; Systemic Lupus Erythematosus; Behçet disease; Sjor
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https://doi.org/10.1007/978-3-540-49695-3r of vessels throughout the body which lead to significant organ involvement. This condition, given its low prevalence, is classified as a rare systemic vasculitis. Although its etiology remains unclear, it is known that it is a multifactorial and immune-mediated disease in which imbalances of the i
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