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Titlebook: Genetics and Product Formation in Streptomyces; Book 1991

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Genetic Characterization and Cloning of Genes for Chlortetracycline Resistance in Streptomyces Aureozed on one long DNA fragment of about 34 kb.. The genes for biosynthesis are flanked by genes responsible for resistance to Otc, . and ., “early” biosynthesis genes being linked to . and “late” genes to .. Coordinated transcription of resistance and biosynthesis genes has been demonstrated.
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Molecular Genetic Investigation of , and , Strains, the Producers of Flavomycin and Tylosinrowning peptidoglycan chain. The flavomycin complex antibiotics have relatively high molecular weight — about 2 kD — and a complicated structure: they contain oligosaccharide, phosphoglyceric acid, a C.-lipid alcohol moenocynol and a UV-chromophore. The genetics of . and moenomycin biosynthesis is not studied well.
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https://doi.org/10.1007/978-3-0348-6724-5affecting mostly ribosomal proteins. This indicates that a certain optimal level of translational fidelity was selected during evolution rather than its maximum level (Ehrenberg .., 1986). The reason for this could be that translational errors may play an important regulation role.
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Presence of Factor C in Streptomycetes and Other Bacteriaconcerning these regulatory processes cannot be overestimated.. A promising field of research is the investigation of those endogenously produced substances (autoregulators) that were shown to influence the differentiation of . (A-factor, B-factor, Pamamycin 607, and factor C, reviewed by Szabó et al..).
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