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Titlebook: Genes and Mechanisms in Vertebrate Sex Determination; Gerd Scherer,Michael Schmid Book 2001 Springer Basel AG 2001 Chromosom.Termination.V

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,,, an “antitestis” gene,opins and adrenal hormones but are sterile. .-deficient females are fertile. The DAX-1 protein, an unusual member of the nuclear hormone receptor, may act as a transcriptional repressor. It has been shown to both repress transcriptional activators by direct protein-protein interactions and to bind DNA hairpin structures and repress target genes.
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Book 2001n gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, a
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Towards Multicultural Education in Finland, than the invertebrates: 60000 vs. 15000. Consequently, each invertebrate gene has been amplified to the maximum of four paralogous genes in vertebrates: the one-to-four rule. When this rule is applied to genes pertinent to gonadal development and differentiation, the following emerged: (i) Two clos
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https://doi.org/10.1007/978-3-030-58900-4s that genetic sex — determined at fertilization by the presence or absence of the Y chromosome — directs the embryonic gonads to differentiate into either testes or ovaries. Thereafter, hormones produced by the testes direct the developmental program that leads to male sexual differentiation. In th
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François Abbé-Decarroux,François Grincription factor that is known to bind to specific target sequences in DNA and to cause a bend in the chromatin. DNA bending appears to be part of the mechanism by which . influences transcription of genes downstream in a cascade of gene regulation leading to maleness, but the factors that cooperate
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https://doi.org/10.1007/978-3-030-38065-6fy genes that are highly conserved in vertebrate sex determination and those that have recently evolved roles in one lineage. Analysis of the conservation and function of candidate sex determining genes in marsupials and monotremes has been crucial to our understanding of their function and position
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