书目名称 | Genes and Mechanisms in Vertebrate Sex Determination | 编辑 | Gerd Scherer,Michael Schmid | 视频video | | 丛书名称 | Experientia Supplementum | 图书封面 |  | 描述 | .Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.. | 出版日期 | Book 2001 | 关键词 | Chromosom; Termination; Vertebrate; chromosome; development; fish; genes; mammals; vertebrates; Model vertebr | 版次 | 1 | doi | https://doi.org/10.1007/978-3-0348-7781-7 | isbn_softcover | 978-3-0348-7783-1 | isbn_ebook | 978-3-0348-7781-7Series ISSN 1664-431X Series E-ISSN 2504-3692 | issn_series | 1664-431X | copyright | Springer Basel AG 2001 |
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