Titlebook: Gene Therapy of Cancer; Methods and Protocol Wolfgang Walther,Ulrike Stein Book 20001st edition The Editor(s) (if applicable) and The Autho

clarify

https://doi.org/10.1007/978-981-15-5228-1The application of antioncogene ribozyme in the gene therapy of breast cancer by means of recombinant adenoviral vector is dicussed in this chapter. We have shown that recombinant adenovirus encoding anti-cerbB2 ribozyme inhibited the breast cancer cell growth in vivo efficiently (.,.). We will talk about the detailed protocol here.

清澈

Anti-,1 Ribozyme Gene TherapyMultidrug resistance (MDR) in human cancer seriously limits the efficacy of anticancer agents. Circumvention of MDR is, thus, one of the urgent goals for successful cancer chemotherapy.

健忘症

Anti-c-,1B2 Ribozyme for Gene Therapy of Breast CancerThe application of antioncogene ribozyme in the gene therapy of breast cancer by means of recombinant adenoviral vector is dicussed in this chapter. We have shown that recombinant adenovirus encoding anti-cerbB2 ribozyme inhibited the breast cancer cell growth in vivo efficiently (.,.). We will talk about the detailed protocol here.

Albinism

Karl Buermeyer,Daniel Reinhart,Kristin Legg to expose host tissues to high cytotoxic plasma drug concentrations. This chapter describes the cytochrome P450-based prodrug activation strategy for cancer gene therapy , with a particular emphasis on the selection of suitable P450 gene/prodrug combinations.

Blood-Vessels

Selection of Cytochrome , Genes for Use in Prodrug Activation-Based Cancer Gene Therapy to expose host tissues to high cytotoxic plasma drug concentrations. This chapter describes the cytochrome P450-based prodrug activation strategy for cancer gene therapy , with a particular emphasis on the selection of suitable P450 gene/prodrug combinations.

突袭

1543-1894 s human diseases, scientists have been fas- nated with the possibility of treating certain diseases by transducing foreign DNA into the affected cells. Initially, it was proposed that the foreign DNA could either replace defective nonfunctional genes, or code for therapeutic proteins. This concept h

Paleontology

Book 20001st edition nated with the possibility of treating certain diseases by transducing foreign DNA into the affected cells. Initially, it was proposed that the foreign DNA could either replace defective nonfunctional genes, or code for therapeutic proteins. This concept has evolved into the rapidly growing field o

肌肉

扫兴

cuticle

Construction of P450-Expressing Tumor Cell Lines Using Retroviruses cytotoxicity assays using these cell lines can then be carried out as described in Chapter 7 prior to initiating more costly and labor intensive in vivo tumor studies in animal models (described in Chapter 8).