Titlebook: Gene Therapy; R. E. Sobol,K. J. Scanlon,E. Nestaas Conference proceedings 1998 Springer-Verlag Berlin Heidelberg 1998 Expression.Gentherap

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Pro-drug Gene Therapy for Prostate Cancer,tatec—tomy are clinically understaged and are postoperatively found to have tumor extension outside the prostate (Ohori et al. 1995; Paulson 1994; Trapasso et al. 1994; Walsh et al. 1994; Zeitman et al. 1994; Zincke et al. 1994).

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https://doi.org/10.1057/978113731336268; Curcio et al. 1997), peptide nucleic acids (Demidov et al. 1993), and aptamers (Stull and Szoka 1995); ribozymes as small RNA molecules with intrinsic specific catalytic activity are one of the most promising candidates for future molecular drugs (Irie et al. 1997).

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0947-6075 for delivering therapeutic genes to diseased cells, viral and non-viral vector systems, are detailed and characterized. Several reports describe both approaches currently used in gene therapy: the introduction of a wild-type gene to restore normal gene function in diseased cells, and the use of ant

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0947-6075 ar diseases, using genetic material as therapeutic agents. The regulatory issues governing the use of gene therapy in Europe and the United States are also presented. This book highlights the range of applications and demonstrates the rapid progress being made in the field of gene therapy.978-3-662-03579-5978-3-662-03577-1Series ISSN 0947-6075