Titlebook: Gene Therapy; Mauro Giacca Textbook 2010 Springer-Verlag Milan 2010 Clinical trials.Gene therapy.Inherited disorders.Molecular genetics.Vi

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Cities’ Sustainability in a Risk-Prone Worldrictly depends upon the efficiency of nucleic acid internalization by the target cells. As a matter of fact, making gene transfer more efficient continues to represent the most relevant challenge to the clinical success of gene therapy.

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Introduction to Gene Therapy, at least two major advancements that were occurring in those years, namely the exponentially growing knowledge of human gene function and the impact of their mutations, and the development of progressively more effective technologies for the delivery of DNA into mammalian cells.

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Introduction to Gene Therapy, at least two major advancements that were occurring in those years, namely the exponentially growing knowledge of human gene function and the impact of their mutations, and the development of progressively more effective technologies for the delivery of DNA into mammalian cells.

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Clinical Applications of Gene Therapy,ing several tens of thousands of patients. If objectively evaluated, the overall clinical success of these trials has been modest so far. With some remarkable exceptions, most of the trials have encountered unanticipated technological and biological problems. In this evaluation, however, it should b