书目名称 | G Protein-Coupled Receptor Screening Assays |
副标题 | Methods and Protocol |
编辑 | Duarte Miguel F. Prazeres,Sofia Aires M. Martins |
视频video | |
概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice.Includes supplementary material: |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | . This volume. .explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound’s efficacy. New discoveries in the field, along with the widely recognized need for better and safer pharmaceutical drugs constitute the main motivation for this book. Readers, both beginners and experienced researchers, will receive an updated overview of not only the established, but also the innovative technologies that promise to advance GPCR drug research. This book is organized into two major parts: the introductory part discusses the necessary foundations for the understanding of GPCR action and the rationale behind the design of the available screening assays; and part two provides detailed protocols for different screening approaches. Written in the highly successful .Methods in Molecular Biology .series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory..Practical and innovative, .G Protein-Coupled Receptor Screening Assays: Metho |
出版日期 | Book 2015 |
关键词 | G-Protein Coupled Receptors; GPCR signaling; GPCR-active drugs; drug research; high content screening; hi |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4939-2336-6 |
isbn_softcover | 978-1-4939-5580-0 |
isbn_ebook | 978-1-4939-2336-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media New York 2015 |