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楼主: 使醉
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Early Biochemical Steps in Colony Stimulating Factor (CSF) Generation are Induced by Synergy betweenhate (InsP3). DAG activates protein kinase C (PK-C) and InsP3 mobilizes intracellular calcium. Both tumor promoting phorbol esters (TPA) which activate PK-C directly and calcium ionophores which mobilize intracellular calcium bypass inositol phospholipid breakdown. We recently reported that the inte
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Establishment of Bone Marrow Stromal Cell Cultures and Permanent Clonal Stromal Cell Lines from Osteutant. The etiology has been presumed due to a defect in the ability the marrow stem cells to differentiate into normally functioning osteoclasts. Data are not available to prove that replacing only the osteoclast precursor (an unidentified cell) will cure the disorder. To test whether marrow stroma
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Monoclonal Antibodies Identify Specific Determinants on Reticular Cells in Murine Embryonic and Adulonstrated by the presence of collagen types I and III and fibronectin, and the absence of collagen type IV and laminin. Three antibodies to these fibroblastoid cells exclusively recognized hemopoietic stromal cells in splenic red pulp and bone marrow of adult mice, with the exception of the occasion
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Stromal Cell Lines from Mouse Bone Marrow: A Model System for the Study of the Hemopoietic Microenvif the stromal tissue which controls hemopoiesis (1–7). It has been, however, impossible to determine conclusively which of the stromal cell types comprising this complex microenvironment tissue is mediating the observed functions. The requirement for pure cell populations for any further experimenta
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Glycosphingolipids as Specific Differentiation-Markers and Differentiation-Inducers for Human Myelogous leukemias and their established cell lines were blocked in cell maturation at certain, recognizable differentiation-steps such as myeloblast or promyelocyte stage. Many research-groups including us have demonstrated that some of them could be induced to differentiate into mature functioning cell
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