Titlebook: Emerging Neurobiology of Antidepressant Treatments; Michael Browning,Philip J. Cowen,Trevor Sharp Book 2024 The Editor(s) (if applicable)

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乐章

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Neuropsychological Effects of Antidepressants: Translational Studies,ntidepressant effects remains largely unknown. With the help of animal models, a detailed understanding of their pharmacological targets and acute and chronic effects on brain chemistry and neuronal function has been achieved, but it remains to be elucidated how these effects translate to clinical e

细胞学

Ketamine for Major Depressive Disorder,me to onset of therapeutic action (approximately 2 weeks) and fails to achieve a stable remission of symptoms in one-third of subjects with MDD. In the last 20 years the discovery of antidepressant effects of the N-methyl-d-aspartate (NMDA) receptor antagonist ketamine as a rapid acting (within hour

细胞学

懒洋洋

Microbiota-Gut-Brain Axis and Antidepressant Treatment,d nonpharmacological interventions such as various kinds of psychotherapy. Over the last 2 decades, there has been considerable interest in the role of the gastrointestinal system and its microbiota on brain function, behavior, and mental health. Components of what is referred to as the microbiota-g

我邪恶

Anti-inflammatory Drugs in the Treatment of Depression,th preclinical and clinical data have highlighted pathways and possible mechanisms that might link changes in immunobiology, most especially inflammation, to clinically relevant behaviour. From a therapeutics perspective, a major impetus has been the action of Biologics, often monoclonal antibodies,

儿童

Mechanisms of Action of TMS in the Treatment of Depression,solateral prefrontal cortex (DLPFC), emerged from early neuroimaging studies in depression. Recently, more rigorous casual methods have revealed whole-brain target networks and anti-networks based on the effects of focal brain lesions and focal brain stimulation on depression symptoms. Symptom impro