Titlebook: Experimental Models of Parkinson’s Disease; Yuzuru Imai Book 2021 The Editor(s) (if applicable) and The Author(s), under exclusive license

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美丽的写

Josef Hoschek,Franz-Josef Schneideruclein and the evaluation of its modifying factors are required to understand the pathogenesis of Parkinson’s disease and to develop new therapies. In this chapter, we describe a cell-based assay for detecting α-synuclein propagation.

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Hyperplasia

Mathematics and its Applicationsice tissues with Sca.eS technique. These include brain slice preparation, tissue clarification, chemical and immunohistochemical labeling (ChemSca.e and AbSca.e), and observation of labeled tissues using a confocal laser scanning microscope (CLSM).

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α-Synuclein Seeding Assay Using Cultured Cellsuclein and the evaluation of its modifying factors are required to understand the pathogenesis of Parkinson’s disease and to develop new therapies. In this chapter, we describe a cell-based assay for detecting α-synuclein propagation.

广口瓶

Midbrain Slice Culture as an Ex Vivo Analysis Platform for Parkinson’s Diseaseowever, some discrepancy is observed in these results. In order to analyze progressive neurodegenerative disease, experimental platform amenable to continuous observation and experimental manipulation is required. In this chapter, we provide a practical method to slice and cultivate the midbrain tissue as an ex vivo experimental model.

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