| 书目名称 | Experimental Models of Parkinson’s Disease | | 编辑 | Yuzuru Imai | | 视频video | | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | This detailed book focuses on cutting-edge methods for Parkinson’s disease (PD) research, such as the analysis of the prion-like properties of α-synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells), deep brain stimulation therapy, classic mitochondrial toxins related to PD, and genetic associations and screenings using mammalian and invertebrate genetic models of PD. The collection intends to serve as an introductory protocol book for basic research on PD pathogenesis. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .Experimental Models of Parkinson‘s Disease. is an ideal guide for researchers continuing to work toward making PD risk predictable and surmountable.. | | 出版日期 | Book 2021 | | 关键词 | PD development; α-Synuclein; Cellular models; Mammalian models; Invertebrate models; Neurodegenerative di | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-0716-1495-2 | | isbn_softcover | 978-1-0716-1497-6 | | isbn_ebook | 978-1-0716-1495-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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发表于 2025-3-21 18:21:30
