Titlebook: Evaluating Evidence of Mechanisms in Medicine; Principles and Proce Veli-Pekka Parkkinen,Christian Wallmann,Jon Willia Book‘‘‘‘‘‘‘‘ 2018 Th

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Evaluating Evidence of Mechanisms in Medicine978-3-319-94610-8Series ISSN 2211-4548 Series E-ISSN 2211-4556

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in such a way as to be regularly or predictably responsible for the phenomenon to be explained) and mechanistic processes (a spatio-temporal pathway along which certain features are propagated from the starting point to the end point). The chapter emphasises that EBM+ is concerned with evidence of

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Economic Rationality and Practical Reason a number of mechanism hypotheses, formulation of review questions for search, and then how to refine and present the resulting evidence. Key issues include increased precision concerning the nature of the hypothesis being examined, attention to differences between the study population (or populatio

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The Paradox of Financial Flows,res of specific mechanism hypotheses, laying out a three step procedure of evaluating: (1) the methods used, (2) the implementation of the methods, and (3), the stability of the results. The next step is to combine those evaluations to present the quality of evidence of the general mechanistic claim

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Uncertainty and Austerity Policy,ation can be combined with an evaluation of evidence for relevant correlations in order to produce an overall evaluation of a causal claim. The procedure is broken down to address efficacy, external validity, and then the overall presentation of the claim.

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https://doi.org/10.1007/978-1-349-22095-3tcomes. It is typically not possible to use RCTs to solve this problem, for ethical reasons. The approach outlined in this book is compared to two other prominent approaches: the procedures of the International Agency for Research on Cancer (IARC), and SYRINA, a framework for detecting exposures tha