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Titlebook: Evaluating Evidence of Mechanisms in Medicine; Principles and Proce Veli-Pekka Parkkinen,Christian Wallmann,Jon Willia Book‘‘‘‘‘‘‘‘ 2018 Th

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发表于 2025-3-21 19:42:36 | 显示全部楼层 |阅读模式
书目名称Evaluating Evidence of Mechanisms in Medicine
副标题Principles and Proce
编辑Veli-Pekka Parkkinen,Christian Wallmann,Jon Willia
视频video
概述The only book to develop explicit procedures for evaluating evidence of mechanisms.Contains a philosophical justification of these procedures.Extends and improves the tools available to Evidence-Based
丛书名称SpringerBriefs in Philosophy
图书封面Titlebook: Evaluating Evidence of Mechanisms in Medicine; Principles and Proce Veli-Pekka Parkkinen,Christian Wallmann,Jon Willia Book‘‘‘‘‘‘‘‘ 2018 Th
描述.This book is open access under a CC BY license. .This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. .Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. . .The bookoffers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental
出版日期Book‘‘‘‘‘‘‘‘ 2018
关键词Evidence-based medicine; Mechanisms in medicine; Evaluating evidence; Medical methodology; Evidence hier
版次1
doihttps://doi.org/10.1007/978-3-319-94610-8
isbn_softcover978-3-319-94609-2
isbn_ebook978-3-319-94610-8Series ISSN 2211-4548 Series E-ISSN 2211-4556
issn_series 2211-4548
copyrightThe Editor(s) (if applicable) and The Author(s) 2018
The information of publication is updating

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发表于 2025-3-21 22:39:55 | 显示全部楼层
An Introduction to Mechanisms in such a way as to be regularly or predictably responsible for the phenomenon to be explained) and mechanistic processes (a spatio-temporal pathway along which certain features are propagated from the starting point to the end point). The chapter emphasises that EBM+ is concerned with evidence of
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How to Consider Evidence of Mechanisms: An Overviewhen external validity (developed theoretically in Part III, with tools for implementation offered in Part II). An outline of quality assessment—of a whole body of evidence, rather than individual studies—is given. The chapter finishes with a brief introduction to the ideas developed in Part III: gat
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Gathering Evidence of Mechanisms a number of mechanism hypotheses, formulation of review questions for search, and then how to refine and present the resulting evidence. Key issues include increased precision concerning the nature of the hypothesis being examined, attention to differences between the study population (or populatio
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Using Evidence of Mechanisms to Evaluate Efficacy and External Validityation can be combined with an evaluation of evidence for relevant correlations in order to produce an overall evaluation of a causal claim. The procedure is broken down to address efficacy, external validity, and then the overall presentation of the claim.
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Assessing Exposurestcomes. It is typically not possible to use RCTs to solve this problem, for ethical reasons. The approach outlined in this book is compared to two other prominent approaches: the procedures of the International Agency for Research on Cancer (IARC), and SYRINA, a framework for detecting exposures tha
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Assessing Mechanisms in Public Health how public health has treated associations and correlations. Then it examines the importance to public health of mechanisms operating at the group and individual level, concerning social interactions and support, access to socio-sanitary infrastructures, psychological factors, and so on, which have
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