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Titlebook: Enzymes in Nonaqueous Solvents; Methods and Protocol Evgeny N. Vulfson,Peter J. Halling,Herbert L. Holl Book 2001 Humana Press 2001 biochem

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发表于 2025-3-21 18:05:45 | 显示全部楼层 |阅读模式
书目名称Enzymes in Nonaqueous Solvents
副标题Methods and Protocol
编辑Evgeny N. Vulfson,Peter J. Halling,Herbert L. Holl
视频video
概述Includes supplementary material:
丛书名称Methods in Biotechnology
图书封面Titlebook: Enzymes in Nonaqueous Solvents; Methods and Protocol Evgeny N. Vulfson,Peter J. Halling,Herbert L. Holl Book 2001 Humana Press 2001 biochem
描述Enzymatic catalysis has gained considerable attention in recent years as an efficient tool in the preparation of natural products, pharmaceuticals, fine chemicals, and food ingredients. The high selectivity and mild reaction con- tions associated with enzymatic transformations have made this approach an attractive alternative in the synthesis of complex bioactive compounds, which are often difficult to obtain by standard chemical routes. However, the maj- ity of organic compounds are not very soluble in water, which was traditi- ally perceived as the only suitable reaction medium for the application of biocatalysts. The realization that most enzymes can function perfectly well under nearly anhydrous conditions and, in addition, display a number of useful properties, e. g. , highly enhanced stability and different selectivity, has d- matically widened the scope of their application to the organic synthesis. Another great attraction of using organic solvents rather than water as a reaction solvent is the ability to perform synthetic transformations with re- tively inexpensive hydrolytic enzymes. It is worth reminding the reader that in vivo, the synthetic and hydrolytic pathways are
出版日期Book 2001
关键词biochemical engineering
版次1
doihttps://doi.org/10.1385/1592591124
isbn_softcover978-1-61737-256-8
isbn_ebook978-1-59259-112-1Series ISSN 1940-6061 Series E-ISSN 1940-607X
issn_series 1940-6061
copyrightHumana Press 2001
The information of publication is updating

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Imprinting Enzymes for Use in Organic Mediactrostatic and hydrogen-bonding interactions among the surface residues of the protein in organic solvents (.). Despite this rigidity, enzymes remain active and selective in organic solvents, and this has led to a large number of applications that have impacted the chemical, pharmaceutical, and poly
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Very High Activity Biocatalysts for Low-Water Systems of magnitude. Because this can make the difference between whether a particular biotransformation is practically useful or not, it is important to control enzyme history carefully. The basic problem is simple: how to transfer the enzyme from an aqueous environment to one where it is dehydrated whil
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