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Titlebook: Endotoxins: Structure, Function and Recognition; Xiaoyuan Wang,Peter J. Quinn Book 2010 Springer Science+Business Media B.V. 2010 Antigen.

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Synthetic and Natural TLR4 Agonists as Safe and Effective Vaccine Adjuvantsated the mechanism of action of TLR4 agonists and structure-function relationships. Moreover, the formulation of TLR4 agonists has been shown to significantly affect the type and magnitude of elicited immune response. TLR4 agonists comprise a promising class of adjuvants for safe and effective vaccines.
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Purification and Characterization of Lipopolysaccharides O-antigen repeats. Lipid A is responsible for the major bioactivity of endotoxin. Because of their specific structure and amphipathic property, purification and analysis of lipopolysaccharides are difficult. In this chapter, we summarize the available approaches for extraction, purification and analysis of lipopolysaccharides.
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,Kapitel 2 (… 1884–1940/2000 …),ll surface and, therefore, structural modifications to the lipopolysaccharide (LPS). In this chapter, we describe the structures of the LPSs from symbiont members of the ., the genetics and mechanism of their biosynthesis, the modifications that occur during symbiosis, and their possible functions.
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The Diversity of the Core Oligosaccharide in Lipopolysaccharidesooligosaccharide with less than fifteen sugars, more conserved in the inner region, proximal to the lipid A, and often carrying non-stoichiometric substitutions leading to variation and micro-heterogeneity. The core oligosaccharide contributes to the bacterial viability and stability of the outer me
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