Titlebook: Endotoxins: Structure, Function and Recognition; Xiaoyuan Wang,Peter J. Quinn Book 2010 Springer Science+Business Media B.V. 2010 Antigen.

紧张过度

,-Regulated Lipopolysaccharide Modificationsades such as two-component regulatory systems to detect and respond to stimuli in the local microenvironment. During infection, environmental sensing allows bacteria to regulate gene expression to evade host immune defenses and thrive in vivo. Activation of the . two-component regulatory systems Pho

Hectic

The Variation of O Antigens in Gram-Negative Bacteriaacteria. It is on the cell surface and appears to be a major target for both immune system and bacteriophages, and therefore becomes one of the most variable cell constituents. The variability of the O antigen provides the major basis for serotyping schemes of Gram-negative bacteria. The genes respo

GLUE

Regulators of TLR4 Signaling by Endotoxinser the past decade have revealed the components involved in these signaling pathways, however, more recently the focus has shifted somewhat towards the components that regulate these pathways. Several regulatory mechanisms, including localisation of components, splice variants and inhibitory molecul

鼓掌

Membrane Partitioning: Is Location Everything When It Comes to Endotoxin Recognition? Lipid rafts are thought to provide a means to explain the spatial segregation of certain signalling pathways emanating from the cell surface. They seem to provide the necessary microenvironment in order for certain specialised signalling events to take place- such as the innate immune recognition.

付出

Limousine

The Role of Endotoxin in Infection: , and ,l compartment and . the intestinal mucosa. Although . causes chronic gastric infection leading to gastritis, peptic ulcers and eventually gastric cancer while . causes acute infection inducing diarrhoeal disease, the endotoxin molecules of both bacterial species contrastingly contribute to their pat

增减字母法

The Role of , Lipopolysaccharide in Cystic Fibrosis Airway Infectionwith impaired phagocytic function, such as those with burns, exposure to chemotherapy, or cystic fibrosis (CF). PA infects the lungs of most individuals with CF, and is associated with severe progressive pulmonary disease that is the major cause of premature death in this disorder. The specific adap

反叛者

Development of Small-Molecule Endotoxin Sequestering Agentspite advances in antimicrobial chemotherapy. The primary trigger in Gram-negative sepsis is endotoxin, a lipopolysaccharide (LPS) constituent of the outer membrane of all Gram-negative bacteria. The structurally highly conserved glycolipid called lipid A is the active moiety of LPS. Lipid A is compo

向外供接触

Development of an Anti-Endotoxin Vaccine for Sepsisin intensive care units. Vaccines directed against core LPS structures that are widely conserved among Gram-negative bacteria (GNB) have been developed for the treatment and/or prevention of sepsis. Killed whole bacterial vaccines (. O111:B4, J5 [Rc chemotype] mutant and ., Re chemotype) protected m

Alveolar-Bone