Titlebook: Endocrine FGFs and Klothos; Makoto Kuro-o Book 2012 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer S

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René König und die "Kölner Schule"ered mineral metabolism and particularly, disordered phosphorus metabolism appears to be a contributing factor. Fibroblast growth factor 23 (FGF23) regulates phosphorus and vitamin D metabolism. Its levels increase progressively beginning in early CKD, presumably as a physiological adaptation to mai

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https://doi.org/10.1007/978-3-662-33866-7and safer drugs. Large molecule therapy has played an important role in diabetes since the discovery of insulin. This legacy was continued upon the introduction of Humulin (first recombinant insulin), Humalog (first engineered insulin) and Byetta (first incretin mimetic). Several other protein thera

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https://doi.org/10.1007/978-1-4614-0887-1Endocrine; FGF; Fibroblast growth factor; Klotho; Kuro-o; gene expression

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