Titlebook: Efflux-Mediated Antimicrobial Resistance in Bacteria; Mechanisms, Regulati Xian-Zhi Li,Christopher A. Elkins,Helen I. Zgurska Book 2016 Spr

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Fluvial and Lacustrine Systems,e of . spp. to antimicrobials including clinically used antibiotics and biocides. This chapter provides an overview of current status of antimicrobial resistance and the contribution of drug efflux pumps to clinically relevant resistance, with a focus on the characteristics of efflux pumps of the resistance-nodulation-cell division superfamily.

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Multidrug Efflux in the Context of Two-Membrane Cell Envelopesbranes of the cell envelope. This chapter focuses on the structures and mechanisms of trans-envelope multidrug efflux pumps from Gram-negative bacteria. We summarize the current state of the field and the emerging model for multidrug efflux in the context of two membranes.

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Antimicrobial Resistance in Bacteria: An Overview of Mechanisms and Role of Drug Efflux Pumpshapter provides an overview of molecular and biochemical mechanisms of antimicrobial resistance with an emphasis on the role of drug efflux pumps and their relationship with other key resistance mechanisms in clinically relevant intrinsic and acquired resistance.

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Book 2016 a particularly powerful mechanism of multidrug resistance, an in-depth examination of efflux pumps is conducted with bacteria of major public health concern including Enterobacteriaceae, .Acinetobacter., .Neisseria., .Pseudomonas., staphylococci, and mycobacteria. The content spans structural bioch

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Small Multidrug Resistance Efflux Pumpss SMR family diversity and reviews current structural and functional knowledge of these members. This chapter also provides an update of known SMR pump-mediated resistance to antimicrobial substrates (including naturally synthesized quaternary cation compounds) and their clinical significance.

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https://doi.org/10.1007/978-981-13-3678-2pite of intense efforts, it is still not clear exactly how multidrug transporters work. In this chapter, we discuss some of the recent advances for multidrug transporters in two important families, the major facilitator superfamily (MFS) and multidrug and toxic compound extrusion (MATE) family.

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