Titlebook: Dynamic-Clamp; From Principles to A Thierry Bal,Alain Destexhe Book 2009 Springer-Verlag New York 2009 Biophysics.Cortex.Neurobiology.Stent

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Frank Ahlhorn,Jenny Kebschull,Helge Bormann a cell, as well as the construction of whole hybrid networks in which the biological cell interacts with model cells simulated in real time using a digital or analog system. Many of the applications briefly presented here are the subject of the following chapters.

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https://doi.org/10.1007/978-3-658-42694-1ed “high-conductance” state, thought to occur in vivo, and suggest alternate means by which coherent activity can be generated in the absence of strong cellular oscillations. We close by discussing future developments that will increase the utility and widespread use of the dynamic-clamp method.

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ies. Third, the dynamic-clamp experiments could re-create “in vivo-like” background synaptic activity by injection of stochastic excitatory and inhibitory conductances, and we showed that this activity profoundly modifies the input–output transfer function of thalamic and cortical neurons. We also i

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Associating Living Cells and Computational Models: an Introduction to Dynamic Clamp Principles and talist, activating and inactivating into the membrane of an intracellularly recorded biological cell. Dynamic clamp relies on the establishing of a loop between the injected current and the recorded membrane potential. In this introductory chapter, we first present the principles of the technique, s

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,Dendritic Dynamic Clamp – A Tool to Study Single Neuron Computation,synaptic input to the site of action potential initiation in the axon. Direct dendritic whole-cell recording techniques have however demonstrated that dendrites are electrically excitable. Recently, the dynamic clamp has been used to simulate synaptic activity at determined dendritic sites in neuron

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Synaptic Conductances and Spike Generation in Cortical Cells,ting membrane potential and spike responses. However, we now have accurate biophysical models of the ionic conductances at the postsynaptic sites of cortical synapses and of the conductances which generate action potentials (APs). Using conductance injection or dynamic clamp, it is possible to injec

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