Titlebook: Dynamic-Clamp; From Principles to A Thierry Bal,Alain Destexhe Book 2009 Springer-Verlag New York 2009 Biophysics.Cortex.Neurobiology.Stent

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Functions of the Persistent Na+ Current in Cortical Neurons Revealed by Dynamic Clamp,ction potential threshold. This current may strongly influence integration and transduction of synaptic input into spike patterns. However, due to the lack of pharmacological tools for selective blockade or enhancement of .., its impact on spike generation has remained enigmatic. By using dynamic cl

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,Using “Hard” Real-Time Dynamic Clamp to Study Cellular and Network Mechanisms of Synchronization inhinal cortex. We find that “hard” real-time dynamic-clamp systems, characterized by very small maximal errors in timing of feedback, are necessary for cases in which fast voltage-gated channels are being mimicked in experiments. Using a hard real-time system to study cellular oscillations in entorhi

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Unraveling the Dynamics of Deep Cerebellar Nucleus Neurons with the Application of Artificial Condu) to explore how spiking in these neurons is controlled by the interaction of synaptic and intrinsic conductances. Besides the application of synaptic- and voltage-gated conductances, we introduce the modeling of an intracellular calcium pool in the real-time loop of the dynamic clamp in order to ap

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Intrinsic and Network Contributions to Reverberatory Activity: Reactive Clamp and Modeling Studies, in vivo, spontaneously or in response to stimulation. We combined computer simulations and in vitro intracellular recording from prefrontal cortical neurons to explore the elicitation, modulation, and termination of these reverberations. In computer simulations, we studied the reverberating activit

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Using the Dynamic Clamp to Explore the Relationship Between Intrinsic Activity and Network Dynamicse propose a novel method using the dynamic clamp to evaluate the intrinsic properties of isolated neurons that replaces conventional methods such as measuring input impedance. Secondly, we construct novel circuits using the dynamic clamp by electrically coupling pairs of pacemakers of rhythmically a

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Re-Creating In Vivo-Like Activity and Investigating the Signal Transfer Capabilities of Neurons: Dyurons, and how these intrinsic properties influence signal integration. More recently, it became clear that the transfer function of neurons also highly depends on the activity of the surrounding network, and in particular on the presence of synaptic background activity. We review here different in

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