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Titlebook: Drugs and Transport Processes; A Symposium B. A. Callingham Textbook 1973Latest edition Institute of Biology Endowment Trust Fund 1973 drug

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Receptors for mercurial and ethacrynic acid inhibition of sodium chloride transportkers, Bresler & Weinberger, 1960) and diuretic doses of mercury do not inactivate canine ATPase (Nechay, Palmer, Chinoy & Posey, 1967). At present it is possible only to challenge the hypothesis by posing additional requirements.
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The location and chemical nature of drug ‘targets’ within the human erythrocyte membranensider two quite independent determinants. The first is the chemical specificity of the interactions of the drug with effector sites. The second, called ‘geographic specificity’ (Rothstein, 1970), is determined by the location of the effector sites in the membrane and the ability of the drug to reac
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Aqueous pores created in thin lipid membranes by the antibiotics nystatin, amphotericin B and gramicrmeability than on two other factors: first, the significant differences between the osmotic permeability coefficient (Pf) and the tagged water permeability coefficient (P.) (for example, Prescott & Zeuthen, 1953; Nevis, 1958) and secondly, the occurrence of water—solute interaction during osmosis (
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