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Titlebook: Drugs and Transport Processes; A Symposium B. A. Callingham Textbook 1973Latest edition Institute of Biology Endowment Trust Fund 1973 drug

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楼主: necrosis
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D,oups (PBSH). Mercury reduces the concentration of renal PBSH of rats (Cafruny, DiStefano & Farah, 1955) and dogs (Cafruny & Farah, 1956). Dimercaprol not only restores the lost PBSH but also abolishes the pharmacological effects of mercurials. By extension, it is proper to postulate that mercurials
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E,h the cell is a highly probable target for its interaction and effect. In the second place, the membrane as the primary diffusion barrier of the cell determines how rapidly and by which routes the drug reaches the interior of the cell. Although the present discussion will deal primarily with the mem
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D,s to produce a wide range of naturally occurring hydrocarbons, among which are the adrenocortical hormones, sex hormones, sterols proper, the cardiac glycosides, the sapogenins, and some alkaloids. Consideration in this paper will be given to the action of representatives of the adrenocortical stero
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J,siderably grown and, for the first time, reasonably reliable experimental data on the penetration characteristics of rapidly permeating anion species such as chloride and the other halides has become available. The expansion of factual knowledge was accompanied by a critical reconsideration of exist
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F,the ions or whether the structures which carry the sites are fixed in the membrane or free to move about. In order to answer these questions and more generally to establish the possible mechanisms for ion transport, it is useful to investigate model systems. Another reason for studying the propertie
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G,f cell membranes. Although this similarity was originally discovered through interest in the mechanism of the action of the antibiotics in uncoupling oxidative phosphorylation, it has much wider implications for theories of membrane structure, suggesting that the lipid bilayer actually does provide
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