Titlebook: Drugs Eicosanoids; Second Messengers. N John Fawcett Wilson Book 1995 Springer Science+Business Media Dordrecht 1995 Chloramphenicol.Methad

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Etorphine,n morphine and its use carries some risk as it can be absorbed through human skin following accidental spillage. It is a drug of dependence but is said to produce less tolerance and respiratory depression than morphine.

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Corporate Training Investment Decisionslogical activity, a longer duration of action, and produces less frequent cardiac complications and hypersensitivity reactions than procainamide. The acetylation of procainamide is subject to genetic polymorphism with 30-40% being converted in fast acetylators. Up to 85% of a dose of acecainide is e

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Corporate Training Investment Decisionsia. Prolonged use may lead to dependence. Biotransformation in the liver is to inactive metabolites which are excreted in urine. The half-life in plasma is about 1.5 hours. Plasma concentrations after a 50 μg/ kg intravenous dose have been measured as 0.54 μg/ml at 1 min falling to 0.038 μg/ml at 1

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Corporate Training Investment DecisionsAmitriptyline is demethylated to nortriptyline and then by several other routes to metabolites excreted in urine. Genetic differences result in considerable inter-individual variation in metabolism, plasma half-life varying from 8 to 51 hours. The therapeutic range in plasma for treatment of endogen

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Deborah E. Belle,Ruth F. Tebbets loop of Henle in the renal tubule. Use is in the treatment of pulmonary oedema in patients with heart or renal failure. The peak effect is within 30 minutes of intravenous or 1 hour of oral administration and diuresis complete within 6 hours. Oral absorption is rapid and complete. The mean peak con

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