Titlebook: Drugs Affecting Lipid Metabolism; Proceedings of the T William L. Holmes (Director),Lars A. Carlson (Prof Conference proceedings 1969 The E

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and , Studies of Plasma Post-Heparin Lipolytic Activity in Subjects with Hyperchylomicronemia (Fat- designation “hyperchylomicronemia” (3) or “fat-induced” lipemia (4). Serum triglyceride levels in these subjects may be reduced by withholding dietary fat (1) or by providing triglycerides containing medium chain length (C. and C.) fatty acids, as the sole source of dietary fat (5).

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Opening Remarks ahead of us. When the First Symposium was held here in 1960, interest in what drugs might do for us by affecting lipid metabolism was certainly lively enough, enough to produce a rewarding program and a respectable volume of Proceedings. Yet, even at that time, I remember consulting the indices of

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Nervous and Pharmacological Regulation of Vascular Reactions in Adipose Tissuephysiological regulation of circulation and metabolism in the intact adipose tissue is less well known. This may be due to the fact that adipose tissue is diffusely distributed in the body and therefore difficult to isolate with blood flow and nervous supply still intact. Recently, however, Heim and

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Evidence That the Rise in Temperature Produced by ,-Amphetamine is Caused by a Peripheral Action of with a peripheral signal to the brain. We became concerned with this problem after the demonstration that the pronounced hyperactivity elicited by large doses of triiodothyronine in mice was markedly reduced by ganglionic blocking agents, such as chlorisondamine. Since amphetamine acts indirectly t

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Effects of Adrenergic Blocking Agents on FFA Mobilization as in vitro. A brief review of well-known data will be given to introduce this subject, following which new evidence will be presented concerning the site and mode of action of various adrenolytics, methoxamine derivatives, and prostaglandin E.. In order to present a comprehensive story this discus

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Factors Modifying the Effect of Prostaglandin E1 on Lipolysis in Adipose Tissue Prostaglandins have been extracted from adipose tissue as well as from other tissues (2,3). Catecholamines and nerve stimulation have been shown to provoke secretion of prostaglandins, e.g., from rat epididymal fat pad in vitro (4). Most of the observations about the activity of prostaglandins in a

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