Titlebook: Drugs Affecting Lipid Metabolism; A. L. Catapano,A. M. Gotto (Chairman),Rodolfo Paol Book 1993 Springer Science+Business Media Dordrecht 1

Glossy

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,The Expression and Regulation of Cholesterol 7α-Hydroxylase,he rat 7α-hydroxylase gene was cloned and several liver specific and ubiquitous regulatory elements were found in the 5’-upstream sequence of the rat gene. Possible mechanisms of regulation of 7α-hydroxylase are proposed.

确定

0928-9550 lipoproteins and coronary heart disease. However, asusually happens in research, many more interesting issues are beingstudied, opening new fields of research for the future. These newadvances, together with the combined efforts of cell biologists andlipoprotein chemists, have set the pace for an e

Transfusion

Ahmed I. Zayed,Gilbert G. Walteransgenic mice has yielded interesting information on the low density lipoprotein-associating function of apoB-100. In future, transgenic animals expressing site-specific mutant apoB molecules will be a valuable tool to study the structure-function relationship of this complex but functionally important protein in lipid metabolism.

Malfunction

The Way They Were,The Way We Areerogenic potential. Increased shunting of cholesteryl esters into triglyceride-rich lipoproteins appears to be related to impaired triglyceride metabolic capacity which is indicated by the fasting lipoprotein constellation most frequently associated with coronary artery disease: low HDL cholesterol and a preponderance of small-sized HDL and LDL.

Armada

The Way They Were,The Way We Areegion of the LPL gene of the propositus revealed a G→C transversion at the 5’ donor splice site of intron 1. We suggest that this mutation is not compatible with normal mRNA processing and it is responsible for the defect in our patient.

Incumbent

kidney

Influence of Atherogenic Lipoproteins on The Thrombotic Potential of Endothelial Cells,to generate and to remove fibrin. The data so far available indicate that atherogenic lipoproteins influence both tissue factor expression and the release of plasminogen activator inhibitor type a by endothelial cells, thus increasing the prothrombotic potential of vascular endothelium.

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Contribution of Helix-Helix Interactions to the Stability of Apolipoprotein-Lipid Complexes,A-I- and apo A-IV-DPPC discoidal complexes, by energy minimisation procedures, suggests that electrostatic interactions between charged residues can significantly contribute to the stability of the apoprotein-lipid complexes.

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Book 1993ng world labortories, represents an authoritative and up-to-dateappraisal of the status of the art and a stimulus to future researchat the laboratory and clinical level in a fascinating area of clinicaland preventive medicine..