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Titlebook: Drugs Affecting Leukotrienes and Other Eicosanoid Pathways; B. Samuelsson,F. Berti,G. P. Velo Book 1985 Plenum Press, New York 1985 Acetyl

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Hypotheses, Questions, and Evidence,o explain such differences between studies where identical assay methods have been used (for example a commercially available TXB. radioimmunoassay); that is, if the obtained data really reflect the endogenous situation.
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Sri Kurniawan,Andrew Arch,Sean-Ryan Smithhe same molecule, the goal of the studies to be reported here is the development of selective inhibitors of the formation of the leukotrienes in the hope that these agents might then be useful in providing the remaining needed element of proof for the role of the leukotrienes in disease.
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Introduction,ortant areas in this development (1). The new knowledge has formed the basis for understanding the role of prostaglandins in many pathophysiological processes and for the therapeutic use of prostaglandins in various diseases.
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Comparative Effects of Leukotrienes in Respiratory Tissue of Various Species,rs, has been proposed as an important mediator of bronchoconstriction in man. These LTs display pronounced spasmogenic and vasoactive properties in various preparations and possess unprecedented potencies in respiratory smooth muscle in particular..
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,The Effect of 9α-Fluorohydrocortisone on the Urinary Excretion of 6-KETO-PGF1α in Man, an increased urinary volume and sodium excretion. At the same time increased renal blood flow, glomerular filtration rate and reduced renal vascular resistance are observedl. Besides the haemodynamic factors, prostaglandins (PGs) and kallikreinkinin system have been suggested as being responsible, at least partly, for the escape phenomenon.
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