Titlebook: Drug Toxicity in Embryonic Development II; Advances in Understa Robert J. Kavlock (Director),George P. Daston Book 1997 Springer-Verlag Ber

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0171-2004 acology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world‘s literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well

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Anticonvulsant Drugs: Mechanisms and Pathogenesis of Teratogenicityidered a high-risk proposition. This is because of the potential increase in seizure frequency throughout pregnancy, labor, and delivery and because of the higher incidence of adverse pregnancy outcomes (T. and R. 1992).

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Epilogue: Experience and Artificeoses of thalidomide were unsuccessful. On the other hand, this substance was responsible for the largest adverse health outcome ever caused by an agent at therapeutic doses and during a short marketing period.

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Antiviral Agentsents arises from the increasing incidences of viral diseases such as genital herpes, cytomegalovirus (CMV) infections in immunocompromised patients, and last but not least the acquired immunodeficiency syndrome (AIDS) epidemic.

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Cardiovascular Active Drugsother organ systems (mainly the central nervous system) such as phenytoin, caffeine, nicotine, and the narcotic drug cocaine also exert pharmacological action on the cardiovascular system as a side effect.

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Book 1997e asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world‘s literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well establish