Titlebook: Drug Studies in the Elderly; Methodological Conce Neal R. Cutler (Director),Prem K. Narang (Supervis Book 1986 Plenum Publishing Corporatio

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H,e of importance in influencing the design and conduct of drug studies. This will be done by briefly examining those physiological changes in humans that might be expected to influence disposition of and response to drugs. This approach is being taken for several reasons.

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N,ne agonists; (4) monoamine oxidase inhibitors; (5) anticholinergic agents; and (6) amantadine. Levodopa is the cornerstone of Parkinsonism disease treatment. The other five drug classes are useful supplements or occasional alternatives to levodopa.

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978-1-4684-1255-0Plenum Publishing Corporation 1986

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Cardiovascular Changes with AgingChanges in cardiovascular anatomy and function that are specifically due to aging are often difficult to distinguish because of the high prevalence of heart and blood vessel disease among the elderly in Western cultures. .

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The Aging BrainThis chapter discusses the relationship between functional alterations and brain metabolism in aging animals and humans and in the pathological conditions of Alzheimer’s disease (AD).

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