Titlebook: Drug Metabolite Isolation and Determination; Eric Reid,J. P. Leppard Book 1983 Plenum Press, New York 1983 carboxylic acid.chromatography.

针叶类的树

Preparative Liquid-Chromatographic Methods in Drug Metabolism Studies isolated in quantities sufficient for full structure elucidation by spectroscopic and chemical methods. It can be applied to complex mixtures of metabolites of widely varying polarities. Since separation is done at low temperature, normally no stability problems arise. Recoveries can easily be checked if radioactively labelled drugs are used.

得罪

Assessment of Radioactivity Measurements on HPLC Effluents.D. of the peak volume should be less than 0.5, to minimize the possible influence of collection regime. With small fractions, however, the long counting periods needed for high sensitivity and precision [3] delay the procurement of the chromatographic results. Off-line counting is also disadvantageous in respect of time and materials costs.

Conflict

The Use of Long Capillary GC Columns for Urinary Phenolic Acids from Catecholamines and Analoguesof these columns and of their use in examining urinary constituents (human, rat) and in metabolic work with compounds related to catecholamines. When measuring previously unauthenticated compounds, identities must be confirmed by independent means because some of the numerous urinary constituents may interfere.

天赋

Horizon

Examples of Approaches to Isolating and Identifying Phase I Metabolites in vivo in the target species, the cow. GC-MS was used to identify drug-derived urinary components that had been isolated by a range of chromatographic procedures. In the study of cloprostenol metabolism the high isotopic abundance of.C in radio-labelled cloprostenol allowed an unusual method of detecting metabolites.

有恶臭

老人病学

VERT

使乳化

Narciso García,Luis Salgado,José M. Martínezer which can quantitate compounds on TLC plates by direct absorption in visible or UV light, by fluorescence quenching (a fluorescent substance being incorporated in the absorbent layer), or by fluorescence emission. Examples are now given.

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