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Titlebook: Discoidin Domain Receptors in Health and Disease; Rafael Fridman,Paul H. Huang Book 2016 Springer Science+Business Media New York 2016 can

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DDRs and Collagen Fibrillogenesisgen fibrillogenesis. We begin with Sect. ., which summarizes the experimental evidence on the role of DDRs in collagen fibrillogenesis. In the most comprehensive Sect. . we describe the various stages of fibrillogenesis of collagen type I with special attention to the putative role(s) of DDRs at eac
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DDR Mouse Modelsnd implantation, as well as wound healing and auditory sensation. In addition, genetically modified mice and DDR mutant mice highlight the role of DDRs in the enhancement or attenuation of diseases, including fibrosis, atherosclerosis, and osteoarthritis in various conditions..Studies on mouse model
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Discoidin Domain Receptor 2 in Development of Osteoarthritisn osteoarthritic joint. If, as we suspect, DDR2 is one of the major contributors to progressive joint failure, then drugs that inhibit the kinase activity of DDR2 may be able to ameliorate osteoarthritis conditions.
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DDR1 in Renal Function and Diseasee pathways were not activated which resulted to an impressive preservation of renal function and structure. Further proof of evidence came from experiments with in vivo administration of antisense oligonucleotides against DDR1. The fact that this pharmacogenetic approach protected animals against th
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