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Titlebook: Diastolic Relaxation of the Heart; Basic Research and C William Grossman (Herman Dana Professor of Medicin Book 1988 Martinus Nijhoff Publi

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Load Dependence of Relaxationpump is thus governed by the dynamic interaction of the sensitivity of the contractile apparatus to the prevailing load (load dependence) and the dissipating activation (inactivation). This interaction is modulated by the regional and temporal nonuniform distribution of load and inactivation.
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Diastolic Myocardial Mechanics and the Regulation of Cardiac Performancees on how the heart adapts to clinical heart disease, and to provide direction for future clinical investigation of myocardial mechanics in humans. This chapter will review these topics primarily through publications from our laboratory, each of which contains full references.
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Functional Sequelae of Diastolic Sarcoplasmic Reticulum Ca2+ Release in the Myocardium. filling rates and volumes, and systolic function still more common. While these technological developments have verified the notion of variable diastolic compliance and the coexistence of “abnormal diastolic” function with normal or abnormal systolic “function,” the nature of the former and its relation to the latter still remain obscure.
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Ischemic/Hypoxic and Reperfusion/Reoxygenation Contractures: Mechanismsamic from myocardial properties are not unique to systolic function. The observation nevertheless marked a renewal of interest in diastolic function whose importance had been rather neglected since before the days of Harvey.
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