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Titlebook: Diastolic Relaxation of the Heart; Basic Research and C William Grossman (Herman Dana Professor of Medicin Book 1988 Martinus Nijhoff Publi

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Diastolic Myocardial Mechanics and the Regulation of Cardiac Performancel and diseased hearts. Very early in our studies, it became evident that existing descriptors of myocardial performance were deficient, and initial efforts were expended to develop basic models of ventricular geometry, diastolic properties, and systolic function. Later work has been directed toward
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Evaluation of Time Course of Left Ventricular Isovolumic Relaxation in Humanslaxation can be approximated by a monoexponential function. Their technique required that the derived or best-fit monoexponential curve for the pressure data decay asymptotically toward zero pressure. [1, 2]. Subsequent evaluation of the time course of pressure fall during isovolumic relaxation has
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Influence of Pressure and Volume Overload on Diastolic Compliancegth relationship. Compliance of the ventricular chamber refers to the ratio of change in volume (dV) to a change in pressure (dP). The reversed ratio represents chamber stiffness (dP/dV). The relationship between P and V throughout diastole is curvilinear. It is popular to fit the P-V data to an exp
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Influence of the Pericardium on Diastolic Complianceiac chambers, and the total volume contained within the cardiac chambers [1]. To illustrate the latter factor, it is reasonable to expect that at a given left ventricular volume, the influence of the pericardium on left ventricular compliance will be directly proportional to the volume contained wit
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