Titlebook: Diabetes Mellitus; A risk factor for Al Yusaku Nakabeppu,Toshiharu Ninomiya Book 2019 Springer Nature Singapore Pte Ltd. 2019 Brain-derived

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,Mammalian Target of Rapamycin at the Crossroad Between Alzheimer’s Disease and Diabetes, Neurology 53(9):1937–1942, 1999; Voisin et al, Rev Med Interne 24(Suppl 3):288s–291s, 2003; Janson et al. Diabetes 53(2):474–481, 2004; Ristow M, J Mol Med (Berl) 82(8):510–529, 2004; Whitmer et al, BMJ 330(7504):1360, 2005, Curr Alzheimer Res 4(2):103–109, 2007; Ohara et al, Neurology 77(12):1126–

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0065-2598 e presented evidence. In providing answers to the critical questions of whether and why DM is a risk factor for AD, this book will hold appeal for a wide interdisciplinary audience. .978-981-13-3540-2Series ISSN 0065-2598 Series E-ISSN 2214-8019

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Scheduling on Parallel Processors,t type 3 diabetes is just one of the categories of insulin resistance diseases that can occur independently or overlap with one or more of the others, including type 2 diabetes, metabolic syndrome, and nonalcoholic fatty liver disease.

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https://doi.org/10.1007/978-3-319-43884-9loid accumulation in the brain, indicating different from AD pathology. In addition to insulin resistance, elevated inflammatory cytokines, oxidative stress, and advanced glycation end products were associated with cognitive impairment in this type of dementia. Glycemic controls can improve some dom

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The Challenge of a 4°C World by 2100 Neurology 53(9):1937–1942, 1999; Voisin et al, Rev Med Interne 24(Suppl 3):288s–291s, 2003; Janson et al. Diabetes 53(2):474–481, 2004; Ristow M, J Mol Med (Berl) 82(8):510–529, 2004; Whitmer et al, BMJ 330(7504):1360, 2005, Curr Alzheimer Res 4(2):103–109, 2007; Ohara et al, Neurology 77(12):1126–

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Book 2019t opens by discussing the de novo synthesis of insulin in the brain and its functional significance with regard to glucose metabolism and maintenance of neuronal function in the brain. The epidemiological evidence that DM is a risk factor for the development of dementia, including AD as well as vasc

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Probing, Inspection, Monitoring balance, as well as plasticity throughout adulthood. Moreover, there are substantial evidence demonstrating that brain insulin is derived from pancreas, neurons, and astrocytes. In this chapter, I reviewed recent progress in roles of insulin in the brain, expression of insulin genes, and multiple origins of the brain insulin.