Titlebook: Designer Receptors Exclusively Activated by Designer Drugs; Gerald Thiel Book 2015 Springer Science+Business Media New York 2015 CNO-stimu

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Book 2015 measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression

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Martina Hujslová,Milan Gryndlerssess the equivalence or otherwise of function of a wild-type and corresponding RASSL receptor. The human muscarinic M. acetylcholine receptor is used as the exemplar but similar preliminary studies should be employed before further use, particularly in vivo, of such RASSLs.

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,Regulation of Gene Transcription Following Stimulation of Gαq-Coupled Designer Receptors,that the reporter genes are embedded into a nucleosomal structure. Recombinant lentiviruses infect mitotic and postmitotic cells such as neurons, thus allowing the analysis of transcriptional changes following the activation of G protein-coupled designer receptors.

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0893-2336 ation advice from the expertsThis volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the u