| 书目名称 | Designer Receptors Exclusively Activated by Designer Drugs |
| 编辑 | Gerald Thiel |
| 视频video | http://file.papertrans.cn/269/268891/268891.mp4 |
| 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
| 丛书名称 | Neuromethods |
| 图书封面 |  |
| 描述 | This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo. Chapters focus on the utility of DREADD technology to selectively stimulate or inhibit neuronal activity in selected brain areas of transgenic mice. In addition, the successful use of DREADD expression in rats and Drosophila is described. Together, the DREADD technology represents a non-invasive, chemical-genetic tool for investigating neuronal signaling and the resulting behavioural responses in vivo. Written in the popular .Neuromethods .series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory. Concise and easy-to-use, .Designer Receptors Exclusively Activated by Designer Drugs .aims to ensure successful results in the further study of this vital field. |
| 出版日期 | Book 2015 |
| 关键词 | CNO-stimulated designer receptors; DREADD; G protein; G-protein coupled receptors; GPCR signaling; design |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-2944-3 |
| isbn_softcover | 978-1-4939-4957-1 |
| isbn_ebook | 978-1-4939-2944-3Series ISSN 0893-2336 Series E-ISSN 1940-6045 |
| issn_series | 0893-2336 |
| copyright | Springer Science+Business Media New York 2015 |
|Archiver|手机版|小黑屋|
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