Titlebook: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy; Emmanuel Donnadieu Book 2016 Springer International Publishing Switz

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Book 2016py is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume

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Emmanuel DonnadieuGives the latest research on specific defects in T cell trafficking, which hinder the success of cancer immunotherapy.Provides the basic priniciples to T cell migration during efficient immune respons

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M. D. Maines,M. J. Tomio,V. Janouseketed immunotherapies. Treatments, such as cancer vaccines, CAR T cells and immune checkpoint inhibitors, aim to activate and harness T cells against cancer. However, tumors induce pathological angiogenesis and, at the same time, condition the tumor blood vessels to form a tumor vascular network that

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