| 书目名称 | Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy |
| 编辑 | Emmanuel Donnadieu |
| 视频video | |
| 概述 | Gives the latest research on specific defects in T cell trafficking, which hinder the success of cancer immunotherapy.Provides the basic priniciples to T cell migration during efficient immune respons |
| 丛书名称 | Resistance to Targeted Anti-Cancer Therapeutics |
| 图书封面 |  |
| 描述 | This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.. |
| 出版日期 | Book 2016 |
| 关键词 | Cancer Treatment; Anti-tumor immune response; Immogenic tumors; Cancer-associated fibroblasts; Cancer-as |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-42223-7 |
| isbn_softcover | 978-3-319-82528-1 |
| isbn_ebook | 978-3-319-42223-7Series ISSN 2196-5501 Series E-ISSN 2196-551X |
| issn_series | 2196-5501 |
| copyright | Springer International Publishing Switzerland 2016 |
发表于 2025-3-21 18:23:41
