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Titlebook: DNA Vaccines; W. Mark Saltzman,Hong Shen,Janet L. Brandsma Book 2006 Humana Press 2006 Antigen.T cell.autoimmunity.cell.molecular biology.

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楼主: 深谋远虑
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Hindi Phoneme Recognition - A Reviewne is a plasmid DNA vector that can be taken up by cells to produce a protein, encoded by the vector, to be targeted for the induction of humoral or cellular responses. Although the intracellular production of the antigen may promote responses, the vectors themselves may display adjuvant activity be
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Aadil Gani Ganie,Samad Dadvandipoure-sticks, and the need for effective mass immunization. Naked DNA vaccines, as attractive and universal as they appear, have not produced robust immune responses in test systems. However, proof of principle for DNA vaccines has been validated with a number of vaccine candidates in a variety of test
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https://doi.org/10.1007/978-3-030-82322-1ions of DNA and multiple doses are required before an effective immune response is detected. To overcome these impediments we have developed approaches to deliver the plasmids via needle-free methods, which have been shown to be more effective than traditional needle and syringe methods. Furthermore
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Alan Bundy,Kwabena Nuamah,Christopher Lucasust enter the cell, navigate its way through endocytic compartments, and ultimately reach the nucleus. Currently, the precise pathway taken by plasmid DNA is not clear. Understanding how plasmid DNA interacts with the cell and which path it follows to reach the nucleus will aid in the rational desig
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Francisco Botana,Zoltán Kovács,Tomás Reciothe Toll-like receptor 9 expressed by B cells and plasmacytoid dendritic cells, and trigger the activation of the innate and adaptive immune system. Upon signaling, CpG DNA induces B cells, natural killer cells, macrophages, and dendritic cells to proliferate, differentiate, take up, and present ant
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Abdulsadek Hassan,Mohammed Angawiity. We developed a novel vaccination strategy that used synthetic, cationic (positively charged), and antigenic peptides complexed to negatively charged nucleic acids: antigenic, major histocompatibility complex-class I-binding epitopes fused with a cationic sequence derived from the HIV tat protei
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Boris Kovalerchuk,Kawa Nazemi,Ebad Banissiox virus (rFPV) vaccines are promising HIV-1 vaccine candidates, although delivering either vaccine alone may be insufficient to induce sufficient T-cell responses. A consecutive immunization strategy, known as “prime-boost,” involving priming with DNA and boosting with rFPV vaccines encoding multip
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