| 书目名称 | DNA Helicases and DNA Motor Proteins |
| 编辑 | Maria Spies |
| 视频video | |
| 概述 | Provides first systematic overview of structure, function and regulation of DNA helicases.Integrates knowledge obtained through diverse technical approaches.Gives a unified view on how helicases funct |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | .In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. .The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in r |
| 出版日期 | Book 2013 |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4614-5037-5 |
| isbn_softcover | 978-1-4899-9851-4 |
| isbn_ebook | 978-1-4614-5037-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
发表于 2025-3-21 16:27:17
