书目名称 | cAMP Signaling | 副标题 | Methods and Protocol | 编辑 | Manuela Zaccolo | 视频video | | 概述 | Includes cutting-edge methods and protocols on cAMP signaling.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This detailed volume encompasses new technological developments that specifically address questions related to adenosine 3′,5′-monophosphate (cAMP) compartmentalization, that probe relevant protein-protein interactions, that increase the spatial and temporal resolution of cAMP signal detection, and that can facilitate integration of the mounting complexity of the information that is becoming available on this signaling system. cAMP, the prototypical intracellular second messenger, regulates a large variety of cellular functions and biological processes, including gene transcription, cell metabolism, proliferation, development, as well as more specialized functions depending on the cell type, so the realization of its extremely complex spatial organization and local regulation is providing novel mechanistic insight into cell physiology and is producing a novel framework for the identification of disease mechanisms. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting an | 出版日期 | Book 2015 | 关键词 | Adenosine 3′,5′-monophosphate; Cellular function; Disease mechanisms; Protein kinase A (PKA); Signaling | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-2537-7 | isbn_softcover | 978-1-4939-4950-2 | isbn_ebook | 978-1-4939-2537-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media New York 2015 |
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