Titlebook: Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment; Nick D. Hadjiliadis Book 1997 Springer Scien

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Gary Phillips,Donald J. Scellato oxidative mechanism of damage caused by Ni(II) binding and reactivity on both genotoxic (DNA) and epigenetic (core histones) levels. Preliminary results of a study of (H3-H4). histone tetramer supporting the validity of CAIH model are also shown.

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Gary Phillips,Donald J. Scellatooth the chemistry of metal ions and the steric requirements of the polypeptide chain as the cause of the diversity of the metal-thiolate cluster structures in MT is discussed. Moreover, a metal-assisted ligand (apoMT) preorganization as a general concept for the formation of MT structure has been proposed.

Measured

Gary Phillips,Donald J. Scellatoion becomes of greater concern in light of a series of studies which shows an increased risk of various neurological disorders, including Alzheimer’s disease (AD) and other skeletal and hematological disorders, associated with elevated Al levels in body fluids and tissues [1–5].

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Diversity of Cluster Structures in Mammalian Metallothionein: Interplay Between Metal Ions and Polypoth the chemistry of metal ions and the steric requirements of the polypeptide chain as the cause of the diversity of the metal-thiolate cluster structures in MT is discussed. Moreover, a metal-assisted ligand (apoMT) preorganization as a general concept for the formation of MT structure has been proposed.

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Interaction of Al(III) with Biomolecules: Bioinorganic Chemistry and Biological Implicationion becomes of greater concern in light of a series of studies which shows an increased risk of various neurological disorders, including Alzheimer’s disease (AD) and other skeletal and hematological disorders, associated with elevated Al levels in body fluids and tissues [1–5].

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