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Titlebook: Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment; Nick D. Hadjiliadis Book 1997 Springer Scien

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书目名称Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment
编辑Nick D. Hadjiliadis
视频videohttp://file.papertrans.cn/243/242697/242697.mp4
丛书名称NATO Science Partnership Subseries: 2
图书封面Titlebook: Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment; Nick D. Hadjiliadis Book 1997 Springer Scien
描述Environmental pollution is one of the main problems to confronthumanity, with the heavy metals occupying a leading role among themost pernicious pollutants. The metals cause cancer and othersicknesses. Their cytotoxic, mutagenic and carcinogenic potentials arenot fully understood, and any thorough investigation demands thecombined efforts of scientists drawn from many different disciplines.But the effects of heavy metals are not all negative: some, like.cis.-DDP, and some ruthenium and tin complexes, have antitumouractivity. .The idea underlying the present work is therefore to present amultidisciplinary perspective on heavy metals in the environment,affording a better understanding of their action on human organismsand health, aiming to make them less polluting and moreenvironmentally friendly.
出版日期Book 1997
关键词Inorganic Chemistry; Nucleotide; carcinogenesis; chemistry; environment; environmental pollution; health; m
版次1
doihttps://doi.org/10.1007/978-94-011-5780-3
isbn_softcover978-94-010-6440-8
isbn_ebook978-94-011-5780-3Series ISSN 1389-1839
issn_series 1389-1839
copyrightSpringer Science+Business Media Dordrecht 1997
The information of publication is updating

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The Oxidative Damage Hypothesis of Metal-Induced Genotoxicity and Carcinogenesisear proteins. The metals, including Ni, Cr, and Co, are capable of causing promutagenic lesions, such as DNA base modifications, inter- and intra-molecular crosslinks of DNA and proteins, DNA strand breaks, rearrangements, and depurination. The underlying mechanisms involve generation of various kin
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Diversity of Cluster Structures in Mammalian Metallothionein: Interplay Between Metal Ions and Polyp for the metal selectivity of clusters and their structural changes upon binding of different divalent metal ions is presented. An interplay between both the chemistry of metal ions and the steric requirements of the polypeptide chain as the cause of the diversity of the metal-thiolate cluster struc
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